Stunning night, with the defeat of #1 Gonzaga by #4 Arkansas and #6 Houston taking down #1 Arizona
| Time | Network | Seed | School | Record | Score | Seed | School | Record | Score | Region |
| 7:00 | CBS | 4 | Arkansas* | 27 – 8 | 74 | 1 | Gonzaga | 28 – 3 | 68 | West |
| 7:29 | TBS | 11 | Michigan | 19 – 14 | 55 | 2 | Villanova* | 28 – 7 | 63 | South |
| 9:39 | CBS | 3 | Texas Tech | 26 – 9 | 73 | 2 | Duke | 29 – 6 | 78 | West |
| 9:59 | TBS | 6 | Houston* | 31 – 5 | 72 | 1 | Arizona | 33 – 3 | 60 | South |
All eyes will be on the bracket busting #15 St. Peter’s game against #3 Purdue. They handily defeated #2 Kentucky 85 – 79 in the first round of the Regional games and favored #7 Murray State 80 – 70 in the second round to make it here tonight. The games is first up at 7:00 PM ET on CBS.
| Time | Network | Seed | School | Record | Score | Seed | School | Record | Score | Region |
| 7:09 | CBS | 15 | St. Peter’s | 21 – 11 | 67 | 3 | Purdue | 29 – 7 | 64 | East |
| 7:29 | TBS | 4 | Providence | 27 – 5 | 61 | 1 | Kansas | 30 – 6 | 66 | Midwest |
| 9:39 | CBS | 8 | N. Carolina | 26 – 9 | 73 | 4 | UCLA | 27 – 7 | 66 | East |
| 9:59 | TBS | 11 | Iowa St | 22 – 12 | 56 | 10 | Miami (FL) | 25 – 10 | 70 | Midwest |
TMC for ek hornbeck